Details of her passing had not been released, but reports stated she died around 2 p.m. Thursday in Van Nuys, California.
"Heaven just got a whole lot funnier" was posted atop a photo of Marie on her website. After five seasons, she moved on to The Doris Day Show.
Rose Marie is survived by her daughter and her son-in-law.
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In recent years, Rose Marie (full name: Rose MarieMazetta) had also garnered new fans, thanks to her Twitter page, according to Entertainment Weekly.
Doris Day, in a rare interview, recalls working alongside "The Dick Van Dyke Show" star Rose Marie on "The Doris Day Show" and how the two have remained friends for almost 50 years. Marie was a comedy writer at the time on the show and said years later, women would come up to her and say, "Thank you for showing me the way". She is the only original cast member to appear on all incarnations of the game show and with all hosts.
As a child performer, she had a successful singing career as Baby Rose Marie.