While the new men have just 11 caps between them, Farrell showed signs of striking up a comfortable partnership with Bundee Aki against Argentina in November and Porter made a big impression after replacing Furlong early on against Italy.
James Ryan is named in the second row with Devin Toner while Peter O'Mahony, Dan Leavy and CJ Stander form the back row trio. Replacements: S Cronin, J McGrath (both Leinster), John Ryan (Munster), Q Roux (Connacht), J Conan (Leinster), K Marmion (Connacht), J Carbery, F McFadden (both Leinster).
"You suddenly have to replace world class players but we're more focussed on who we do have - and who we do have is Andrew Porter who is a really promising young player that we're excited about". We thought on Tuesday Tadhg would make it but his progress stalled and we want to get him right for Scotland in a couple of weeks. "I'm obviously not going to explain them".
The New Zealander, who coached the two Irish players during the British and Irish Lions tour of New Zealand previous year, said the key was to attack them.
The Wales team sees the return of three Lions in Dan Biggar, Leigh Halfpenny and Liam Williams and Schmidt acknowledged there is no better setting for Porter, Ryan and Farrell to learn.
Avani Chaturvedi: First woman to fly a solo fighter jet
Mohana Singh and Bhawana have also completed training to fly a fighter plane and will soon fly fighter planes. It was in October 2015 that the Indian Government took the decision to open the fighter stream for women.
Ahead of Saturday's chance to avenge last season's loss to Wales, though, Schmidt finally accepted Ireland have developed their attacking approach.
The British and Irish Lions No.10 will make his first appearance for Wales in this year's Six Nations after suffering a shoulder injury playing for his club Ospreys in the European Rugby Champions Cup against Clermont Auvergne in January.
"This year it's more than 60 per cent - they don't give the ball away - and we're going to maintain our discipline and intelligent aggression at the breakdown and tackle area".
"We have a plan and the players will work hard to put it in place".
England won their opening two matches of this year's competition, against Italy and Wales.