Those strikes destroyed an airstrip, aircraft and fuel stations, and were retaliation for another chemical gas attack at Khan Sheikhoun, that killed around 90 people, an attack the United Nations later officially blamed on Syrian forces.
Syrian TV is reporting that the attack on Syria targeted a scientific research center in Barzeh, near Damascus.
While there had been general public warnings broadcast by U.S. President Donald Trump, Macron himself and other Western leaders, a French presidency source clarified that the French leader did not tell Russian President Vladimir Putin the allies would strike overnight when they talked over the phone on Friday. As he spoke, explosions rocked Damascus.
The US launched airstrikes on Syria over Syrian President Bashar al-Assad's alleged use of chemical weapons in Damascus.
On Monday, Russia warned that any military intervention from the US against Russian allies in Syria would result in the "most serious consequences" and called news of last weekend's chemical attacks "fabricated".
"The objective of our actions tonight is to establish a strong deterrent against the production, spread and use of chemical weapons", Trump said.
North Atlantic Treaty Organisation members Germany and the Netherlands have said they will not take part in any military action. "They are crimes of a monster instead".
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Syrian state TV showed supporters of President Bashar al Assad honking their vehicle horns, waving Syrian flags and parading through iconic squares and arteries of the capital Damascus Saturday morning. A second witness said the Barzah district of Damascus had been hit in the strikes. "We are not ruling out sarin right now", Mattis said.
Mrs May said "every possible diplomatic channel" had been explored before authorising the strikes, adding that it was not a decision she had taken lightly.
Syrian television reported that Syria's air defenses, which are substantial, responded to the attack.
U.S. Senator Elzabeth Warren question Trump's legitimacy to carry out further military action without Congressional approval writing, "The Constitution gives Congress the power to authorize military action". However, Syrian air defense systems intercepted the majority of the attempted strikes, according to the Russian Defense Ministry. The missiles had been shot down in the Kiswah area south of the capital Damascus, it said.
A chemical weapons storage facility, located west of Homs.
President Trump declared "mission accomplished" Saturday after US military forces carried out missile strikes with Britain and France against Syrian chemical-weapons facilities. Aided by Iran and Russia, Mr Assad has been winning for some time.
Last year, the United States fired 59 Tomahawk cruise missiles from the guided missile destroyers USS Porter and the USS Ross that struck the Shayrat air base. He criticized the US and its allies for launching the strike without waiting for inspectors from the worldwide chemical weapons watchdog to visit the area.