Anderson died at his home in Asheville, North Carolina.
Anderson then went on to land his most well-known role, playing Judge Harry T. Stone on Night Court, which aired on NBC from 1984-92.
Police were called to his home before 8 a.m. Monday morning.
No foul play is suspected. In a Gambit preview of Anderson's 2005 one-man show "Wise Guy", David Lee Simmons wrote, "When Anderson says he wants to bring some of the magic back to the French Quarter - where he once roamed as a street performer in the "70s before Night Court and Dave's World - he also means the magic of bygone eras". The series lasted four seasons on CBS.
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He is survived by his wife, Elizabeth Morgan, and he had two children from a previous marriage, according to IMDB.
Before "Night Court", Anderson played Harry, a small-time con man and semi-regular patron at the bar in "Cheers". He starred in several other TV specials and shows, including roles on "Saturday Night Live" and "Cheers". Night Court somehow still feels like an unheralded part of TV history, a show that has a loyal audience from its original run but still doesn't seem like it receives the attention that it deserves. "Rest in peace, Harry". "I tip my hat to you, my friend". The interview is in my book Sick In The Head. "RIP Harry... You made me laugh out loud", one fan tweeted regarding the news. It was a dream come true. If you're not familiar, google him.
Neil Patrick Harris revealed that he recently bought magic memorabilia from Anderson, including a phone booth with the actor's name on it.
Our thoughts and condolences go out to Anderson's family, friends, and fans during what has to be an incredibly hard time.