The 47-year-old is one of a handful of serious contenders for the job, which will become available once Wenger steps aside at the end of the season. During his reign at Atletico, he has taken the club to a La Liga title and two Champions League finals; despite lacking the financial power of Real Madrid and Barcelona. What exactly is that opportunity?
The Europa League is Arsenal's only hope of securing silverware this season.
The playmaker sat out of Sunday afternoon's 4-1 win over West Ham though and that has put his involvement against Atletico in doubt. So they have to have a manager who can punch above their weight, and the outstanding candidate for me is Diego Simeone at Atletico Madrid.
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Atletico Madrid sit in second spot in La Liga with four games left to play, eleven points behind Barcelona and four ahead of city rivals Real Madrid. £150m, £200m ploughed into the team each season.
According to Spanish publication AS, Liverpool, Arsenal, Paris Saint-Germain and Juventus are all monitoring Atletico Madrid's Jan Oblak. But I dispute that strongly.
What is the team news?"That's hard, and you need a special type of manager to do that".
Arsenal could be handed a potential boost by Simeone's decision to switch up his side, while also taking confidence from key man Diego Costa's absence for the first leg.