Mr Pompeo's speech did not specifically call for regime change in Iran but he did go as far as urging Iranian people not to put up with their leaders, naming President Hassan Rouhani and Foreign Minister Mohammad Javad Zarif.
All of these appeasement nods would somehow work out, the Barack Obama team said, because we would build better relations with Iran over time and we've got a good inspection regime. "These will end up being the strongest sanctions in history when they are complete". The law would prevent European companies from complying with USA sanctions.
"Over the past four decades, the Islamic republic has resisted the US and its allies' plots and has turned out victorious", he said, adding that likewise, the Islamic republic will abort the USA hostile policies in the future as well.
Though some European businesses have said they will comply with the US demands and stop doing business with Iran, some European leaders have threatened countermeasures to offset the effects of USA sanctions.
"Who are you to decide for Iran and the world?"
"Iran will never again have carte blanche to dominate the Middle East", Pompeo said, outlining 12 tough conditions from Washington for any "new deal" with Tehran.
That said, Pompeo's expectation about Iran's treatment of its own people was not included in his list of 12 demands of the Iranian regime if they wish to rejoin the worldwide community.
The Trump administration has vowed to reimpose sanctions that were lifted as part of the 2015 nuclear agreement, which was signed between Iran, the United States, and several European countries, as well as Russian Federation and China.
We will track down Iranian operatives and their Hezbollah proxies operating around the world and crush them.
She also noted that International Atomic Energy Agency (IAEA) has on multiple occasions confirmed that Iran has implemented "all its nuclear related commitments" under the agreement. The requirement that nuclear inspectors get universal access would include military sites - long a red line for the regime.
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"Iran will never again have carte blanche to dominate the Middle East", he said in outlining the new USA strategy on handling the Islamic regime, including 12 tough conditions from Washington for any "new deal" with Teheran.
"Iranians shouldn't play into the challenges and US radicalism", Heshmatollah Falahatpisheh told the Iranian Students News agency.
At the same time, the founding director of the Democracy Institute said that Iran would be unwilling to renegotiate the nuclear deal as it is satisfied with the existing terms.
The demands ranged from ending military aid to Middle East militias and closing down its ballistic-missile program to permanently abandoning uranium enrichment and releasing all foreign detainees.
"US diplomacy sham is merely a regression to old habits: imprisoned by delusions & failed policies-dictated by corrupt Special Interest-it repeats the same wrong choices and will thus reap the same ill rewards".
President Donald Trump's decision to ditch the Iranian nuclear deal was supposed to terrify Tehran into surrendering its nuclear program and cleaning up its behavior around the region. "But not its actions which jeopardize the world's citizens".
Pompeo also assailed the "fatal flaws" of the 2015 nuclear agreement, brokered by the Obama Administration in two years of intense negotiations. In that crisis, the administration says it won't accept a strategy of synchronized, step-by-step concessions in exchange for North Korea gradually giving into demands to give up its nuclear program. As the Associated Press reported, "Taken together, the demands would constitute a wholesale transformation by Iran's government, and they hardened the perception that what Trump's administration really seeks is a change in the Iranian regime".
"The prospect of a new jumbo Iran treaty is going to be very, very hard", said the United Kingdom foreign secretary, Boris Johnson, after Pompeo's speech.
As for the consequences, Pompeo was vague, saying only that Iran would be met with "steely resolve" if it continues on its current course.
The secretary also made an explicit appeal to the Iranian people.